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 Answer BOF 160

 

   

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BOF 160
Myelodysplastic syndromes, all are true except
1-seen increasingly in old people but no age is exempted
2-cytopenias are very common and dysplastic changes in the bone marrow are seen
3-up to 40 % will progress to AML
4-5q- syndrome has a relatively good prognosis and is seen mainly in woman
5-the commonest type is refractory anaemia

Answer 5
1-true mainly it is a disease of elderly
2-like hypo granular neutrophils, abnormal neutrophil nuclear lobulation, vacuolated erythroblasts
3-other causes of death are from infection and bleeding
4-and secondary MDS is seen after chemotherapy and radiotherapy
5-false the majority is refractory anaemia with excess blasts in transformation

Revision Tip

Revise MDS KEYS to SUCCESS in Medicine page 364-365

 



 

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