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 Best of Five 28

 

   

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BOF: 28

A 30-year-old female presents with a history of weakness and fatigability of the ocular, bulbar and limb muscles. On examination she has bilateral ptosis and extra-ocular muscle weakness. Reflexes are preserved, there is no muscle wasting. The Edrophonium test is positive.

In this patient

a)      Thymectomy has no long term benefit

b)      If a thymoma is present the muscle weakness would improve

c)      In non-thymoma patients improvement will be seen in 60 % of patients

d)      The prognosis is worse as the patient is under 40 years of age

e)      Thymectomy should not be performed if the patient has positive receptor antibodies

 

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