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 Best of Five 3.126

 

   

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BOF: 3.126

A 74 year old male presents with a history of breathlessness. He has mild diet controlled diabetes mellitus but apart from this he had been reasonably well. He smoked 10 cigarettes a day and consumed 12 units of alcohol per week. He was a retired lawyer.

On examination he did not appear to have lost weight, he looked pale and there was generalised lymphadenopathy and splenomegaly.

Investigations

Hb 6.3 g/dL

WBC 120 x109 /L

Platelets 45 x109/L

Blood film showed mainly mature lymphocytes

In this patient which one of the following would you commence?

a)      Prednisolone

b)      Vincristine, prednisolone , doxorubicin , cyclophosphamide

c)      Melphalan

d)     Mustine, oncovin , procarbazine , prednisolone

e)      Hydroxyurea

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