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 Best of Five 3.58

 

   

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BOF: 3.58

 

A 27-year-old female presents with a history of an itchy, blistering rash. On examination you note multiple small, clustered vesicles over the elbows, knees and buttocks.

There are multiple excoriations around the lesions.

You arrange a skin biopsy. The skin biopsy is likely to reveal:

 

a)      IgG deposition on the surface of the keratinocytes in and around lesions

 

b)      Granular IgA deposits in dermal papillae of perilesional skin observed by direct immunofluorescence

 

c)      IgG and complement C3 deposition in a linear band at the dermal-epidermal junction

 

d)      Immunoglobulin G and complement in a linear or granular bandlike pattern at the basement membrane zone

 

e)      Infiltration of lymphocytes at the dermal-epidermal interface with accompanying exocytosis and spongiosis in the epidermis

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