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 Best of Five 3.81

 

   

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BOF: 3.81

A 65-year-old male presents with a history of fatigue, breathlessness on exertion on exertion, dizziness, fever and bleeding gums.

On examination he is found to have hepatosplenomegaly. Investigations reveal anaemia and thrombocytopaenia. The blood film shows circulating blasts. His lactate dehydrogenase level is elevated and he also has an elevated uric acid level. Bone marrow aspiration shows 30% blasts in the bone marrow.

In this patient the best determinant of prognosis is:

a)      Cytogenetic studies

 

b)      Lactate dehydrogenase levels

 

c)      Number of blasts in the bone marrow

 

d)      White cell count at time of diagnosis

 

e)      Degree of anaemia at time of diagnosis

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