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BOF: 82

A 35-year-old male intravenous drug abuser presents to his GP with a complaint of severe fatigue and a blistering eruption on the sun exposed areas of his skin. He also abuses alcohol consuming between 30-40 units a week. The GP carries out blood test and refers him for investigation of abnormal liver function tests.

In this patient:

a)      Combination therapy will induce a response in 90% of patients

b)      Development of cirrhosis does not preclude a good response to treatment

c)      If the patient develops cirrhosis he has an 80-90% chance of developing hepatocellular carcinoma.

d)      Without treatment end stage liver failure will develop in 2-3 years

e)      In patients without cirrhosis, combination therapy induces a response in 45% of patients

 

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