A 40-year-old female is admitted with a history of
haematemesis and melaena. Apart from an itch, she had previously been well.
She was not on any medication. She smoked 5 cigarettes a day and drank 8 units
of alcohol per week.
On examination her skin looked pigmented, there were
xanthelasma on her eyelids. Her liver and spleen were enlarged. There were no
other abnormalities detected on examination.
Hb 12.8 g/dL
WBC 6.0 x109 /L
Sodium 138 mmols/L
Potassium 4.2 mmols/L
Urea 12 mmols/L
Corrected calcium 1.9 mmol/L
Phosphate 0.6 mmol/L
Glucose 5.3 mmol/L
Bilirubin 12 mmol/L
ALT 32 U/L
Alkaline phosphatase 300 U/L
In this patient which one of the following would give you
AMA (antimitochondrial antibody)
SMA (smooth muscle antibody)
LKM (liver kidney antibody)
SLP/LP soluble liver antigen