A 24 year old female presents with a
history of loss of weight and amenorrhoea. She has a normal appetite and
dietary intake appears adequate. There is no significant past medical history
and she was not on any medications.
On examination she looked underweight
but apart from that there were no abnormalities detectable.
Hb 9.5 g/Dl
MCV 106 fl
WBC 4.3 x109/L
Calcium 1.9 mmol /L
Phosphate 0.74 mmol/L
Alkaline phosphatase 320 U/L
In this patient which of the following
investigations is most likely to suggest the diagnosis?
Tissue transglutaminase antibody
Glucose tolerance test