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BOF: 9

A 56 year old male is reviewed in the hypertension clinic. His hypertension is well controlled on bendroflumethiazide. Routine biochemistry shows his potassium level to be 3.2 mmol /L

Which of the following best describes the mechanism by which bendroflumethiazide causes hypokalaemia?

a)   Increased filtration of potassium through the glomerulus

b)   Increased amounts of sodium reaching the distal tubules

c)    Direct action on potassium co-transporter

d)   Inhibition of the renin angiotensin aldosterone system

e)   Inhibition of anti diuretic hormone

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