Lower limb weakness
Hereditary motor sensory neuropathy
Cauda equina lesion
Spinal cord compression
Subacute combined degeneration of the cord
Motor neurone disease
1) A 26-year-old female with spastic paraparesis and
2) A 65-year-old female with lower limb weakness, with
absent ankle jerks and upgoing plantar response. There is loss of joint
position sense and vibration sense in both feet.
3) A 75-year-old male with prostate cancer presents with
backache and evidence of a spastic paraparesis and incontinence of urine and
4) A 28-year-old female presents with rapidly progressive
weakness in her lower limbs. There is a history of a diarrhoeal illness
preceding the onset of the problem. On examination she has a flaccid weakness
and tendon reflexes are absent.
5) A 50-year-old man with spastic paraparesis,
exaggerated reflexes and upgoing plantars. The upper limb muscles are wasted
and show fasiculations. No sensory involvement.